Sunday, June 26, 2011

Thalassemia patient



I received a mail from a reader regarding Thalassemia patient dietary guide, I have deal with this kind of cases before and I don't mind to share it to all littlediet fans. 
Thalassemia is an inherited autosomal recessive blood disease, to make it simple, there are 2 types of case. The first one is thalassemia major (2 defective genes which need undergo therapy) and the second one is minor (carriers, no symptoms). If the patient is received blood transfusion, then they may need to control the intake of high iron foods. This is related with iron overload problem if blood transfusion but at the same time consumption of high iron foods. Thalassemia is a type of anemia disease. The early destruction of red blood cells cause the oxygen unable be sent to tissues and cells. That's why they need on blood transfusion. The example of high iron foods: seafoods (squid, clams, oysters), internal organs (liver, small intestine, brain), fish roe, raisin, beans, spinach, appropriate amount of chicken, beef and pork. Some of them may also take zinc supplement to chelate (compete) binding with iron to remove excess iron. Besides, patients are encouraged to take tea, coffee, milk, carbonated drink together with meal time to avoid iron absorption. However, they need to avoid taking rich vitamin c  (fruit juice, orange yellow fruits) together with meal as it encourages iron absorption.


地中海贫血可以是一种隐性遗传血液病简单的说,它可分为两种第一个是较严重地中海贫血需要接受治疗,第二种是轻微带菌者,无自觉症状)。如果病人接受输血那么他们可能需要控制高铁质的食物摄入量。地中海贫血是一种贫血的类型,红血细胞的早期破坏导致氧气无法被发送到组织和细胞,这就是为什么他们需要输血海产品鱿鱼,牡蛎(肝,小肠,脑内脏鱼子葡萄干,豆类,菠菜鸡肉,牛肉和猪肉适量都是高铁的食物例子。其中可能需要补充螯合物,以除去多余的铁结合此外,患者用餐时应尝试咖啡,牛奶等饮料,避免铁的吸收。他们也必须避免吸丰富的维生素C(果汁黄色的水果),因为它鼓励铁的吸收。

2 comments:

  1. What if the person is only a carrier??
    This means that they have a low amount of haemoglobin right?? and they will have to increase the amount of haemoglobin...
    Then should they consume food which is high in iron??

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  2. For minor thalassemia, Hb level will be low due to microcyctic anemia which have smaller red blood cells. However, they should not necessary avoid iron rich foods but also need to aware with iron supplements. They may need to meet with physician if appear anemia symptoms to get further investigation through blood test (ferritin level). If no symptoms, he/she can take normal diet with appropriate portion of iron sources foods.

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